How the Data is Collected
Introduction
Survival Rates 1996 - 2006
Patient Survival by Organ
Graft Survival by Organ
How the Data is Collected
Data about the survival rates of organ transplant recipients in the United States is collected by the Scientific Registry of Transplant Recipients (SRTR) in collaboration with the Organ Procurement and Transplantation Network (OPTN) under contract with the Health Resources and Services Administration (HRSA).
Introduction
As of the end of 2005 there were 163,631 persons living with a functioning organ transplant in the United States. This number reflects an increase of 2.1% over the prior year and a 1.6-fold increase since 1997.
According to the 2007 Clinical Transplants Book, the following were the longest-surviving organ transplant recipients in the United States at the time of the report:
| Kidney (LRD) |
44 years, 11 months University of Colorado - Denver |
| Kidney (CAD) |
39 years, 9 months Royal North Shore Hospital |
| Liver |
37 years, 11 months University of Colorado - Denver |
| Heart |
28 years, 4 months Stanford University Medical center |
| Lung (single) |
20 years, 3 months Toronto General Hospital |
| Lung (double) |
20 years, 11 months Toronto General Hospital |
| Pancreas |
24 years, 8 months Thomas E Starzl Transplant Institute |
The total number of organs transplanted annually increased from 27,530 in 2005 to 28,291 in 2006, an increase of 761 (2.8%). This overall increase is attributable to different levels of transplant activity by organ. There was a 7.4% increase in deceased donor kidney transplants.
Other data according to the 2007 Clinical Transplants Book:
Notable changes from 2005 to 2006 also include a 2.3% increase in liver transplants, which occurred despite a decrease in living donor liver procedures that year.
Lung transplantation remained stable, while heart transplantation increased 4.1%.
Percentage declines in transplantation for pancreas, intestine, and heart-lung reflect relatively small changes in the numbers of transplants.
The 28,291 organs transplanted in 2006 came from 14,756 organ donors, 265 more donors than there were in 2005 (2%). The year-over-year increase in the total number of donors resulted from a substantial increase in deceased donors (431, or 6%) and a slight decrease in living donors (166, or 2%).
The number of living donors in 2006 was observed to be lower than any year since 2002. The overall 5.1% increase in organ recovery in 2006 was driven primarily by the 7.3% increase in recovered kidneys. Increases were also seen in liver, heart and lung procurement, while pancreas and intestine procurement remained relatively stable.
Survival Rates 1996 - 2006
Survival rate tables from 1996 to 2006 are provided in the 2007 Organ Procurement and Transplantation Network (OPTN)/ Scientific Registry of Transplant Recipients (SRTR) Annual Report.
Patient Survival by Organ
Here is a table showing Unadjusted* One- and Five-Year Patient Survival by Organ; and Unadjusted One- and Five-Year Graft Survival by Organ (Source: 2007 Organ Procurement and Transplantation Network (OPTN)/ Scientific Registry of Transplant Recipients (SRTR) Annual Report)
| Table 1. Unadjusted One- and Five-Year Patient Survival by Organ |
| Organ Transplanted |
1-Year Survival |
5-Year Survival |
| Kidney |
|
|
| Deceased Donor |
94.8% |
80.6% |
| Living Donor |
98.0% |
90.3% |
| Pancreas alone |
96.7% |
88.1% |
| Pancreas after kidney |
96.6% |
83.9% |
| Kidney-pancreas |
95.0% |
86.1% |
| Liver |
|
|
| Deceased donor |
86.9% |
73.6% |
| Living donor |
90.6% |
76.1% |
| Intestine |
81.0% |
53.6% |
| Heart |
87.8% |
74.4% |
| Lung |
84.0% |
52.6% |
| Heart-Lung |
75.0% |
49.7% |
| Source: 2007 OPTN/SRTR Annual Report, Table 1.13. |
PATIENT SURVIVAL BY ORGAN: Download this table [PDF]
Graft Survival by Organ
This table shows the percentage of transplanted organs that were still functioning (graft survival) one and five years after transplantation, by organ.
Graft survival was calculated using the same cohorts as patient survival (Table 1), the most recent cohorts for which adequate follow-up data are available.
More than 90% of kidneys transplanted alone or as part of a kidney-pancreas transplant were functioning one year after transplantation. Graft survival rates were lower than corresponding patient survival rates because some patients survived graft failure by receiving a subsequent transplant or alternative therapy such as dialysis or insulin therapy.
| Table 2. Unadjusted One- and Five-Year Graft Survival by Organ |
| Organ Transplanted |
1-Year Survival |
5-Year Survival |
| Kidney |
|
|
| Deceased Donor |
90.0% |
67.5% |
| Living Donor |
97.3% |
80.2% |
| Pancreas alone |
80.1% |
50.6% |
| Pancreas after kidney |
78.5% |
58.1% |
| Kidney-pancreas (kidney) |
92.9% |
77.9% |
| Kidney-pancreas (pancreas) |
86.2% |
72.5% |
| Liver |
|
|
| Deceased donor |
82.3% |
67.6% |
| Living donor |
84.1% |
68.6% |
| Intestine |
73.4% |
36.9% |
| Heart |
87.3% |
73.2% |
| Lung |
82.3% |
49.7% |
| Heart-Lung |
75.0% |
73.2% |
| Source: 2007 OPTN/SRTR Annual Report, Table 1.13. |
GRAFT SURVIVAL BY ORGAN: Download this table [PDF]
CHART: ADJUSTED* SURVIVAL RATES SHOWING PERCENTAGE OF GRAFT SURVIVAL
Download a PDF version of this chart [PDF]
*UNADJUSTED AND ADJUSTED SURVIVAL RATES
Unadjusted Survival Rate: The unadjusted survival rate calculations were performed using the LIFETEST statistical procedure. Survival rates were estimated using the Kaplan-Meier method, and standard errors were estimated using Greenwood's formula.
Adjusted Survival Rate: Survival rates are adjusted to allow the reader to compare rates across years. The adjusted rates shown reflect what the survival rate would be if the patient case mix was the same in all years as it was in the last year. The adjusted survival rate calculations are performed using a Cox proportional hazards regression model for time to graft failure or death. This involves using the PHREG statistical procedure. Possible adjustments include age, gender, race, and diagnosis. Table 3 indicates, by organ type, the adjustments that are applied.
In the organ-specific sections, the adjusted survival tables only report rates by age, gender, race, and diagnosis. Here the rates in each table are adjusted for the characteristics other than those of the table itself (for example, kidney survival by age is adjusted for gender, race, and diagnosis). For pediatric patients (i. e., under 12 for lung and under 18 for all other organs), the adjustment by diagnosis is not applied.
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